基于光控蛋白质相互作用的光遗传学技术及其应用
Optogenetics Based on Light-Gated Protein-Protein Interactions and Its Applications
基于光控蛋白质相互作用的光遗传学技术及其应用 |
Optogenetics Based on Light-Gated Protein-Protein Interactions and Its Applications |
| Corelets系统示意图。 Corelets 系统包括两个模块:第一个是GFP标记的24个可光激活的iLID连接组成的铁蛋白核心; 第二个是带有mCherry的结合蛋白SspB,并与固有无序蛋白区域IDR缀合。 虚线表示光诱导异源二聚体单元 |
| Schematic diagram of the Corelets system. Corelets system consists of two modules: a GFP-tagged ferritin core functionalized by 24 photoactivatable iLID domains and iLID's cognate partner, sspB, mCherry-tagged and conjugated to IDR. Dashed lines designate light-inducible hetero-dimerizing units |
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